Driclor

GSK

Description

Driclor acts locally, in the stratum corneum and the terminal duct to relieve hyperhidrosis. Aluminium chloride hexahydrate is acidic and is thought to act by diffusing into the sweat ducts where on neutralisation it forms gelatinous hydroxides which obstruct the flow of sweat. The antiperspirant effect of aluminium chloride hexahydrate is partly explained by production of mechanical blockage in the eccrine sweat duct. Following application, aluminium is found in the stratum corneum and intra-luminally in the terminal duct