Lilly
Lilly
Lilly House
Basing View
Basingstoke
Hampshire
UK
RG21 4FA
01256315000
The professional's guide to product selection
Lilly
Lilly House
Basing View
Basingstoke
Hampshire
UK
RG21 4FA
01256315000
Baricitinib is a selective and reversible inhibitor of Janus kinase (JAK)1 and JAK2. In isolated enzyme assays, baricitinib inhibited the activities of JAK1, JAK2, Tyrosine Kinase 2 and JAK3 with IC50 values of 5.9, 5.7, 53 and > 400 nM, respectiv…
Ixekizumab is an IgG4 monoclonal antibody that binds with high affinity (<3 pM) and specificity to interleukin 17A (both IL-17A and IL-17A/F). Elevated concentrations of IL-17A have been implicated in the pathogenesis of psoriasis by promoting ker…