Products

Guselkumab (Tremfya)

Guselkumab is a human IgG1λ monoclonal antibody (mAb) that binds selectively to the interleukin 23 (IL-23) protein with high specificity and affinity. IL-23, a regulatory cytokine, affects the differentiation, expansion and survival of T cell subsets and innate immune cell subsets, which represent sources of effector cytokines, including IL-17A, IL-17F and IL-22 that drive inflammatory disease. Levels of IL-23 are elevated in the skin of patients with plaque psoriasis. In in vitro models, guselkumab was shown to inhibit the bioactivity of IL-23 by blocking its interaction with cell surface IL-23 receptor, disrupting IL-23-mediated signaling, activation and cytokine cascades. Guselkumab exerts clinical effects in plaque psoriasis through blockade of the IL-23 cytokine pathway.

Hedrin

Hedrin solution contains dimeticone, which is used in many pharmaceutical and cosmetic preparations. A 4% concentration has been found to affect the physico-physiological activity of lice. It is less effective in its ovicidal activity and therefore two applications, 7 days apart, are required. It contains no neurotoxic organophosphate insecticides and acts by a physical process that covers the lice and disrupts their ability to manage their water balance so that treated insects fail to excrete surplus water. Its activity is not diminished in insecticide-resistant head lice

Hydromol Bath & Shower Emollient

An emollient bath additive and soap substitute, with light liquid paraffin 37.8% and isopropyl myristate 13%, that contains no known sensitizers.

Hydromol Cream

Formulation containing sodium pyrrolidone carboxylate 2.5%, a powerful humectant that helps to restore the skin’s natural hydrating properties.

Hydromol Intensive

Contains yellow soft paraffin 32%, emulsifying wax 25.5% and liquid paraffin 42.5%. Intensive therapy for clinically dry skin and eczema with multi-modal hydrating action to complement Complete Emollient Therapy.

Hydromol Ointment

A 3-in-1, all‐purpose emollient, bath additive and soap substitute, which contains no fragrances, colourings, additives or preservatives and is suitable for all ages.

Hydromol Relief Cream

Non-steroidal cream designed to relieve the symptoms and signs of eczema (atopic dermatitis), allergic dermatitis (contact dermatitis) and psoriasis. Contains sodium hyaluronate, vitis vinifera seed extract and shea butter, which, when combined, forms an occlusive barrier; attracts moisture to the skin to help restore the skins natural barrier; and has an antioxidant action to help protect the skin barrier.