Dermatology Handbook

The professional's guide to product selection

Products

Germolene Antiseptic Cream

Germolene Antiseptic Cream

Combines an antiseptic action of phenol and chlorhexidine digluconate to help prevent infections, plus a soothing local anaesthetic effect of phenol to numb the pain.

Germolene Wound Care

A gentle but effective treatment for minor abrasions, wounds, scrapes, burns, bites and stings. The cream contains chlorhexidine dihydrochloride, a mild antiseptic that aids in infection prevention. The cream base softens the skin while also soothing inflammation.

Gluco Allpresean Cream

Diabetic foot foam cream formula forms finely meshed “netting” over the skin which not only protects it from harmful external factors, but the skin is able to breathe and its natural functions are retained.

Guselkumab (Tremfya)

Guselkumab is a human IgG1λ monoclonal antibody (mAb) that binds selectively to the interleukin 23 (IL-23) protein with high specificity and affinity. IL-23, a regulatory cytokine, affects the differentiation, expansion and survival of T cell subsets and innate immune cell subsets, which represent sources of effector cytokines, including IL-17A, IL-17F and IL-22 that drive inflammatory disease. Levels of IL-23 are elevated in the skin of patients with plaque psoriasis. In in vitro models, guselkumab was shown to inhibit the bioactivity of IL-23 by blocking its interaction with cell surface IL-23 receptor, disrupting IL-23-mediated signaling, activation and cytokine cascades. Guselkumab exerts clinical effects in plaque psoriasis through blockade of the IL-23 cytokine pathway.

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