Epiduo Gel
Epiduo contains a combination of adapalene and benzoyl peroxide. Adapalene is a retinoid-like compound that is a potent modulator of cellular differentiation and keratinisation and has anti-inflammatory properties. This profile suggests that the cell-mediated inflammatory component of acne is reduced by adapalene. Benzoyl peroxide has been shown to have antimicrobial activity, particularly against Propionibacterium acnes, which is abnormally present in the acne-affected pilosebaceous unit. In addition, benzoyl peroxide has demonstrated exfoliative and keratolytic activities and is sebostatic, counteracting the excessive sebum production associated with acne