Pro-Sil Gel
Silicone stick that features patented silicone scar therapy technology, delivering scar management with a glide-on applicator makes treating your scars easier.
The professional's guide to product selection
The professional's guide to product selection
Silicone stick that features patented silicone scar therapy technology, delivering scar management with a glide-on applicator makes treating your scars easier.
The mechanism of action of tacrolimus in atopic dermatitis is not fully understood. Whilethe following have been observed, the clinical significance of these observations in atopicdermatitis is not known. Via its binding to a specific cytoplasmic immunophilin (FKBP12),tacrolimus inhibits calcium-dependent signal transduction pathways in T cells, therebypreventing the transcription and synthesis of IL-2, IL-3, IL-4, IL-5 and other cytokines such asGM-CSF, TNF-α and IFN-γ. In patients with atopic dermatitis, improvement of skin lesionsduring treatment with tacrolimus ointment was associated with reduced Fc receptorexpression on Langerhans cells and a reduction of their hyperstimulatory activity towards Tcells. Tacrolimus ointment does not affect collagen synthesis in humans.
Psoriderm Cream is a coal tar preparation. Coal tar has been used dermatologically for hundreds of years and has been shown to be safe and effective in the treatment of scaly skin conditions such as psoriasis. The precise mechanism of action of coal tar is not understood, largely as a result of it comprising up to 10,000 components. There is evidence that topical application of coal tar improves psoriasis by reducing the excessive rate of mitotic epidermal cell division.